What is brittle bone disease type 1?

What is brittle bone disease type 1?

Type 1 OI is the mildest and most common form of brittle bone disease. In this type of brittle bone disease, your body produces quality collagen but not enough of it. This results in mildly fragile bones. Children with type 1 OI typically have bone fractures due to mild traumas.

What is osteogenesis imperfecta Type 2?

OI type II is the most severe type of osteogenesis imperfecta. Affected infants often experience life-threatening complications at birth or shortly after. Infants with OI type II have low birth weight, abnormally short arms and legs and blue sclera.

Is osteogenesis imperfecta Type 1 inherited?

Osteogenesis imperfecta (OI) types I, II, III, IV, V and VI, are inherited in an autosomal dominant manner. This means that having only one changed ( mutated ) copy of the responsible gene in each cell is enough to cause features of OI.

What osteogenesis imperfecta means?

Osteogenesis imperfecta (OI) is an inherited (genetic) bone disorder that is present at birth. It is also known as brittle bone disease. A child born with OI may have soft bones that break (fracture) easily, bones that are not formed normally, and other problems. Signs and symptoms may range from mild to severe.

Is Osteogenesis Imperfecta a type of dwarfism?

Osteogenesis imperfecta (OI) Type III is a dwarfism condition, with adults generally reaching a height of three feet, although profound short stature is often associated with the other three types as well. Hearing loss is common among adults.

Can you grow out of osteogenesis imperfecta?

OI is a childhood disorder; people grow out of it by their teens. FACT: OI is a genetic disorder that is present throughout a person’s lifetime. Many people with OI have fewer fractures after puberty when growth stops, but the genetic difference remains.

How long can you live with osteogenesis imperfecta?

Life expectancy for males with OI was 9.5 years shorter than that for the general population (72.4 years vs 81.9 years), and for females, was 7.1 years shorter than that for the general population (77.4 years vs 84.5 years).

How long do you live with osteogenesis imperfecta?

Is OI progressive?

Osteogenesis imperfecta is a progressive condition that needs life-long management to prevent deformity and complications. The interdisciplinary health care team helps the family to improve the child’s functional outcomes and to provide support to the parents as they learn to care for their child’s needs.

What is OI type 3 severe?

Type III osteogenesis imperfecta — people with type III OI usually will be shorter than their peers, and may have severe bone deformities, breathing problems (which can be life-threatening), brittle teeth, a curved spine, ribcage deformities, and other problems.