What is an oncocytic lesion?

What is an oncocytic lesion?

Nodular oncocytic hyperplasia is a nonneoplastic epithelial lesion. It is most often seen in the parotid, and in the 5th, and 6th decades of life. Nodular oncocytic hyperplasia is a proliferation of oncocytic cells in multiple capsule-free solid – tubule-trabecular pattern.

What is oncocytic metaplasia?

Oncocytic metaplasia is a microscopic feature characterized by the presence of cells with finely granular eosinophilic cytoplasm due to an accumulation of mitochondria. Oncocytes can be observed in normal tissues such as parathyroid, salivary, lacrimal, and mucous glands of the gastrointestinal tract.

What is oncocytic renal neoplasm?

Oncocytoma is a term generally used to describe a neoplasm of the renal parenchyma consisting of well-differentiated cells with prominently eosinophilic granular cytoplasm. We report our experience with such tumors and with 4 cases of granular cell carcinoma (grade 2).

What does Oncocytic change mean?

Oncocytic change is defined as cellular enlargement characterised by an abundant eosinophilic granular cytoplasm as a result of the accumulation of altered mitochondria. This is a phenomenon of metaplasia that occurs in inflammatory disorders, such as thyroiditis, or other situations that result in cellular stress.

How common are Oncocytomas?

Renal oncocytomas are common benign kidney neoplasms that account for 3 to 7 percent of renal neoplasms. They usually occur in adults, most frequently in the seventh decade of life. Renal oncocytomas may be discovered incidentally or may be diagnosed with biopsy or excision.

Is oncocytoma malignant?

An oncocytoma is a tumor made up of oncocytes, epithelial cells characterized by an excessive amount of mitochondria, resulting in an abundant acidophilic, granular cytoplasm. The cells and the tumor that they compose are often benign but sometimes may be premalignant or malignant.

What does oncocytic change mean?

What is an Oncocyte?

Oncocytes are cells that have abundant eosinophilic cytoplasm due to the accumulation of mitochondria; they are also known as oxyphils.