What is the structure of p-nitrophenol on?
4-Nitrophenol (also called p-nitrophenol or 4-hydroxynitrobenzene) is a phenolic compound that has a nitro group at the opposite position of the hydroxyl group on the benzene ring.
What is the pKa of 4-Nitrophenol?
7.15
1) 4-nitrophenol (1) has a pKa of 7.15, while 3-nitrophenol (2) is slightly less acidic with a pKa of 8.36.
Is nitrophenol poisonous?
Contact may severely irritate skin and eyes. Poisonous by ingestion and moderately toxic by skin contact. Acute (short-term) inhalation or ingestion of 4-nitrophenol in humans causes headaches, drowsiness, nausea, and cyanosis (blue color in lips, ears, and fingernails). Contact with eyes causes irritation in humans.
What is the pKa value of nitrophenol?
pKa value of nitrophenol is 7.15. Lower the pKa value stronger is the acid. If nitrophenol has to dissolved in bicarbonate then bicarbonate has to abstract a proton from nitrophenol to from nitrophenolate which is soluble.
How is 4-nitrophenol used as a pH indicator?
4-Nitrophenol can be used as a pH indicator. A solution of 4-nitrophenol appears colorless below pH 5.4 and yellow above pH 7.5. This color-changing property makes this compound useful as a pH indicator.
Which is more acidic O or p nitrophenol?
Nitro in ortho position can hydrogen bond with the phenolic hydroxyl group and consequently the proton is not given out easily making it less acidic than p-nitrophenol. This effect dominates all the above effects and hence p-nitrophenol is more acidic than o-nitrophenol.
Is the phenol 4-nitrophenol poisonous to humans?
Poisonous by ingestion and moderately toxic by skin contact. 4-nitrophenol is a member of the class of 4-nitrophenols that is phenol in which the hydrogen that is para to the hydroxy group has been replaced by a nitro group. It has a role as a human xenobiotic metabolite and a mouse metabolite.