Can lenalidomide cure MDS?

Can lenalidomide cure MDS?

Lenalidomide is taken to help increase blood cell counts, reduce the amount of blood transfusions needed, and to prevent MDS from transforming to acute leukemia. Lenalidomide is not commonly given with the goal of cure for MDS.

How does lenalidomide work in MDS?

In MDS with non-del(5q), lenalidomide acts by modifying bone marrow microenvironment, which abolishes the function of pro-apoptotic and pro-inflammatory cytokines an increased expression of adhesion and restoring erythropoiesis via erythropoietin (EPO)-induced activation of signal transducer and activator of …

What does REVLIMID do for MDS?

REVLIMID® treats the type of MDS where part of chromosome 5 is missing. This type of MDS is known as deletion 5q (del 5q) MDS. Patients with this type of MDS may have low red blood cell counts that require treatment with blood transfusions.

What does REVLIMID target?

Revlimid, also known as lenalidomide, is an oral cancer drug that is used for the treatment of multiple myeloma. It is part of a class of drugs called immunomodulatory drugs (IMiDs), which work against cancer cells partly by supporting the function of the immune system. Revlimid is manufactured by Celgene.

Does REVLIMID cause low white blood cell count?

REVLIMID causes low white blood cells and low platelets in most people. You may need a blood transfusion or certain medicines if your blood counts drop too low.

How long do you stay on Revlimid?

Results showed that patients receiving Revlimid lived 39 months without their disease worsening, compared with 20 months for the observation arm. This translated into a 54% reduction in the risk of disease progression or death.

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