What class of medication is Ranexa?
Ranolazine is in a class of medications called anti-anginals.
What exactly does Ranexa do?
What is RANEXA? RANEXA is a prescription medicine used to treat angina that keeps coming back (chronic angina). RANEXA may be used with other medicines that are used for heart problems and blood pressure control.
What is the mechanism of action for Ranexa?
Mechanism of action Ranolazine inhibits persistent or late inward sodium current (INa) in heart muscle in a variety of voltage-gated sodium channels. Inhibiting that current leads to reductions in intracellular calcium levels.
What are side effects of Ranexa?
- Bloating or swelling of the face, arms, hands, lower legs, or feet.
- continuous ringing or buzzing or other unexplained noise in the ears.
- difficult or labored breathing.
- fast, irregular, pounding, or racing heartbeat or pulse.
- rapid weight gain.
- tingling of the hands or feet.
Is Ranexa bad for kidneys?
It does not commonly cause kidney problems.
What happens if you stop taking Ranexa?
Do not suddenly stop taking this medication without consulting your doctor. Your condition may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased. Inform your doctor if your condition does not improve or if it worsens (such as if your chest pain happens more often).
Can Ranexa cause weight gain?
Weight gain is not a typical side effect of ranolazine (Ranexa).
Which agents should be avoided in a patient receiving ranolazine?
Do not use ranolazine together with carbamazepine (Tegretol®), clarithromycin (Biaxin®), nefazodone (Serzone®), phenobarbital, phenytoin (Dilantin®), rifabutin (Mycobutin®), rifampin (Rifadin®, Rimactane®), rifapentine (Priftin®), medicine to treat fungus infections (eg, itraconazole, ketoconazole, Nizoral®, Sporanox®) …
Does Ranexa lower blood pressure?
Ranolazine (Ranexa) does not typically affect blood pressure like many other anti-angina medications. It can rarely cause low blood pressure.
Can you just stop taking Ranexa?
When should I stop taking Ranexa?
You should stop taking Ranexa and see your doctor immediately if you experience the following symptoms of angioedema, which is a rare condition but can be severe: swollen face, tongue, or throat. difficulty swallowing. hives or difficulty breathing.
Who should not take Ranexa?
Do not use RANEXA with strong CYP3A inhibitors, including ketoconazole, itraconazole, clarithromycin, nefazodone, nelfinavir, ritonavir, indinavir, and saquinavir [see CONTRAINDICATIONS, CLINICAL PHARMACOLOGY].
How Ranexa works for treating angina?
Ranexa (ranolazine) is used to treat chronic angina (chest pain). It works by improving blood flow to help the heart work more efficiently. Ranexa is not for use during an acute (emergency) attack of angina.
How does Ranexa stop angina?
The chief utility of Ranexa is in the treatment of a person with chronic, stable angina. Ranexa can significantly reduce the frequency of angina episodes and increases the amount of exercise that can be performed without experiencing angina. It is usually combined with more standard anti-anginal drug therapy.
When does Ranexa go generic?
The first patent for Ranexa is set to expire in May 2019. This is the earliest possible date that a generic version could become available. However, other circumstances could come up to delay or shorten this exclusivity period. This could include things such as lawsuits or other patents for new Ranexa uses.
What is Ranexa 500 mg?
Ranexa 500 Mg. Ranexa ® (ranolazine) is a prescription medicine used in the treatment of chronic angina (chest pain).