Is multicystic dysplastic kidney hereditary?
There are rare cases when multicystic dysplastic kidney runs in families because of a genetic trait. However, the vast majority occur as a sporadic event. The proper formation of a kidney is complex with hundreds of thousands of steps that must execute correctly.
How common is bilateral multicystic dysplastic kidney?
MCDK happens when fluid-filled pockets (called cysts) replace the healthy kidney tissue. It can happen in one (called “unilateral”) or both (called “bilateral”) kidneys. MCDK happens in about 1 in 1,000 (0.1%) to 4,300 (0.023%) babies.
Can a baby survive with only one kidney?
Many children with only one kidney have no symptoms or complications and do not need treatment. Sometimes the other kidney grows larger than normal to make up for the missing kidney. However, children may be at risk of urinary tract infections (UTIs) and/or hypertension (high blood pressure) later in life.
How common is renal dysplasia?
Kidney dysplasia is a common condition. Scientists estimate that kidney dysplasia affects about one in 4,000 babies. This estimate may be low because some people with kidney dysplasia are never diagnosed with the condition. About half of the babies diagnosed with this condition have other urinary tract defects.
Can MCDK go away?
There is no treatment for MCDK. Most babies with unilateral MCDK go on to live normal, healthy lives. Your baby will see a pediatric urologist or a pediatric nephrologist as they grow up.
What are the side effects of only having one kidney?
Most people with a single kidney live a normal life without developing any long- or short-term problems. However, the risk of developing mild high blood pressure, fluid retention, and proteinuria is slightly higher if you have one kidney instead of two.
What causes a multicystic dysplastic kidney ( MCDK )?
A multicystic dysplastic kidney (MCDK) is the result of abnormal fetal development of the kidney.
Is there a cure for multicystic dysplastic kidney?
The multicystic dysplastic kidney requires no specific treatment. Over time, the abnormal kidney regresses and just goes away. Many people know someone who “only has one kidney.” These are often individuals who had a multicystic dysplastic kidney that shrank and vanished before a doctor could diagnose it.
Is there a link between autism and polycystic kidney disease?
Polycystic kidney disease is associated with significant complications such as hypertension (high blood pressure) and decreased kidney function or kidney failure. Sometimes dialysis or kidney transplant are required. There is no known relationship between multicystic dysplastic kidney and autism.
Can a mutation in the HNF1B gene cause MCDK?
Mutations in the HNF1B gene (17q12), coding for hepatocyte nuclear transcription factor 1β, are known to cause unilateral MCDK and have only rarely been reported for bilateral cases. MCDK is also linked to gestational diabetes and to the use of some medications during pregnancy, such as anti-epileptic drugs.