What is the lipid polymer?
A lipid is a polymer composed of three fatty acid molecules and one glycerol molecule. Lipids produce a special polymer form which is considered to be a key component of cell membranes and hormones. Lipids help to store energy, provide cushion, protect tissues, separate the body, and form membranes of cells.
What is lipid Polymer Hybrid nanoparticles?
Lipid-polymer hybrid nanoparticles (LPNs) are core-shell nanoparticle structures comprising polymer cores and lipid/lipid-PEG shells, which exhibit complementary characteristics of both polymeric nanoparticles and liposomes, particularly in terms of their physical stability and biocompatibility.
What are polymeric nanoparticles?
Polymeric nanoparticles (NPs) are particles within the size range from 1 to 1000 nm and can be loaded with active compounds entrapped within or surface-adsorbed onto the polymeric core. Polymeric NPs have shown great potential for targeted delivery of drugs for the treatment of several diseases.
How do you make lipid nanoparticles?
The lipid nuclic acid nanoparticles were prepared from a liquid nanophase containing water and a water miscible organic solvent where both lipid and DNA are separately dissolved by removing the organic solvent, stable and homogeneously sized lipid-nuclic acid nanoparticle (70-100 nm) were formed.
What is an example of a lipid polymer?
Lipids: water-insoluble molecules that can be classified as fats, phospholipids, waxes, and steroids. Fatty acids form complex polymers such as triglycerides, phospholipids, and waxes. Steroids are not considered true lipid polymers because their molecules do not form a fatty acid chain.
What are polymeric nanoparticles used for?
Polymeric nanoparticles are able to control drug release either by diffusion through polymer matrix or by matrix degradation. They have been investigated as drug-delivery systems for the site-specific targeting of tumors and for the transport of drugs across biological barriers, particularly the blood–brain barrier.
What is the major advantage of polymers in polymeric nanoparticles?
The polymeric nanoparticles are commonly 10-1000nm in size. The polymeric nanoparticles are formulated by drug with the polymers. The main advantages of the polymeric nanoparticles are the simplest preparation method, targeted delivery, the minimizing of the dose and high therapeutic efficiency.
Why are solid lipids nanoparticles?
Advantages of SLNs include the use of physiological lipids (which decreases the danger of acute and chronic toxicity), the avoidance of organic solvents, a potential wide application spectrum (dermal, per os, intravenous) and the high pressure homogenization as an established production method.
What is meant by lipid?
A lipid is chemically defined as a substance that is insoluble in water and soluble in alcohol, ether, and chloroform. Lipids are an important component of living cells. Together with carbohydrates and proteins, lipids are the main constituents of plant and animal cells. Cholesterol and triglycerides are lipids.