Is right-sided colon cancer worse than left-sided?
The authors conclude that patients with right-sided colon cancer have a worse prognosis than those with left-sided colon cancer, even after adjustment for American Joint Committee on Cancer stage, tumor grade, number of lymph nodes examined, year of diagnosis and patients’ demographic variables.
Is there a difference between right versus left-sided colon cancers does side make any difference in long term follow up?
Conclusion: This analysis provides evidence that the prognosis of localized left-sided colon cancer is better compared to right-sided colon cancer. Also, the patients with right colon cancer have more advanced stage, mucinous tumor and are older.
What are the symptoms of right-sided colon cancer?
On the other hand, right-sided colon lesions may produce vague abdominal aching, but are unlikely to present with obstruction or altered bowel habit. Other symptoms such as weakness, weight loss, or anemia resulting from chronic blood loss may accompany cancer of the right side of the colon.
Why is right-sided colon cancer worse?
Patients with right-sided colon cancer had more advanced tumor stages, higher T-stages, had more regional lymph nodes retrieved, a higher grading, more often mucinous carcinomas, were more often Caucasian or African-American, were older, less often married, and were more often female (all P < 0.001).
Where does right sided colon cancer spread to?
The most common sites of distant metastasis are the liver, lungs, and brain. Rectal cancer can spread to adjacent organs in the pelvic region, such as the ovaries or the prostate.
Is there a right and left colon?
The right colon consists of the cecum, ascending colon, hepatic flexure and the right half of the transverse colon. The left colon consists of the left half of the transverse colon, splenic flexure, descending colon, and sigmoid.
What is the difference between right and left colon?
Right-sided colon cancer (RCC) originates from the midgut, including the cecum, ascending colon, and hepatic flexure. In contrast, left-sided colon cancer (LCC) originates from the hindgut, including the splenic flexure, descending colon, and sigmoid colon [3].
Is there a left and right colon?
The right colon consists of the cecum, ascending colon, hepatic flexure and the right half of the transverse colon. The left colon consists of the left half of the transverse colon, splenic flexure, descending colon, and sigmoid. See Figure 1.
How common is right sided colon cancer?
The mean age for the onset of the disease is 16 years, but can occur early at 8 years of age. The number and size of polyps increase with time. Most of the CRC (about 70%) tend to occur in the left side, whereas, a small percentage (about 10%) occurs in the right side [38, 39].
Are right sided colon cancers more aggressive?
Right-sided colon cancers are more aggressive and are associated with poorer clinical outcome as compared to left sided colon cancers in our population.
Is right sided colon cancer hereditary?
Hereditary cancer syndromes except familial adenomatous polyposis (FAP) tend to occur in the right side of the colon. Hereditary non polyposis colorectal cancer (HNPCC) or Lynch syndrome is the most common form of hereditary CRC, observed in 1-6% of all CRC cases.
Are right-sided colon cancers more aggressive?