How does an injection of dexamethasone work?
Dexamethasone injection is in a class of medications called corticosteroids. It works to treat people with low levels of corticosteroids by replacing steroids that are normally produced naturally by the body. It also works to treat other conditions by reducing swelling and redness and by changing the way the immune system works.
What is the bioavailability of oral dexamethasone?
The AUC ratio of 6 mg oral and 4 mg intravenous dexamethasone was 1.22 (95% confidence interval (CI) 0.81, 1.82), which represents a bioavailability of 81% (95% CI 54, 121) after correction for differences in dexamethasone dose. Conclusions: Bioavailability of oral dexamethasone in patients hospitalized with pneumonia is sufficient.
What kind of diseases can dexamethasone be used for?
Dexamethasone is used to treat many different inflammatory conditions such as allergic disorders and skin conditions. Dexamethasone is also used to treat ulcerative colitis, arthritis, lupus, psoriasis, and breathing disorders.
Are there any side effects to taking dexamethasone?
increased blood pressure – severe headache, blurred vision, pounding in your neck or ears, anxiety, nosebleed. Dexamethasone can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine. Common dexamethasone side effects may include: fluid retention (swelling in your hands or ankles);
Where are the hydroxy groups in dexamethasone?
Dexamethasone is a fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids.
How is the dexamethasone suppression test ( DST ) used?
The dexamethasone suppression test (DST) is used in the evaluation of endogenous Cushing syndrome (CS), by assessing for the lack of suppression of the hypothalamic-pituitary-adrenal (HPA) axis by exogenous corticosteroids.
Where can I find dexamethasone in PubChem CID?
Dexamethasone PubChem CID 5743 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS Molecular Formula C22H29FO5 Synonyms dexamethasone 50-02-2 Decadron Maxidex .
What is the proper use of dexamethasone intensol?
Proper Use. The Dexamethasone Intensol™ solution is a concentrated liquid. Measure the concentrated liquid with the special oral dropper that comes with the package. The liquid should be added to water, juice, soda or a soda-like beverage, applesauce, or pudding. Stir the mixture well and drink or eat it right away.
What are the risks of a dexamethasone suppression test?
Dexamethasone suppression test – Other risks associated with having blood drawn are slight, but may include 1 Excessive bleeding. 2 Fainting or feeling lightheaded. 3 Hematoma (blood accumulating under the skin). 4 Infection (a slight risk any time the skin is broken).