What does a high chromogranin a test mean?

What does a high chromogranin a test mean?

CgA levels may be elevated in conditions such as liver disease, inflammatory bowel disease, pancreatitis, chronic bronchitis, renal insufficiency, and stress. These possible causes for elevated CgA levels should be considered when interpreting test results.

What does chromogranin positive mean?

Adrenal system tumors that stain positive for chromogranin A include pheochromocytoma. Lung tumors include small cell cancer. Elevation in serum CgA correlates with the size, extension and the histopathology of the neuroendocrine tumors; it is usually higher in large, metastatic, and well-differentiated tumors.

What is normal chromogranin A level?

There is a normal level of Chromogranin A in the blood, and the range currently is less than 39ng/l.. Abnormal levels can vary form forty to the thousands. The sensitivity of the test for CgA is about 80%, this means that 80% of the time abnormal levels are correctly associated with disease.

What happens if Chromogranin is high?

Impaired kidney function. Elevated CgA also occurs in the case of impaired kidney function due to reduced renal clearance. The higher the degree of renal failure, the higher the CgA concentration, and the result may reach the level found in neuroendocrine tumors [13].

What to avoid before chromogranin a test?

Elevated levels of 5-HIAA suggest a neuroendocrine tumor is present. You will be advised to avoid foods like bananas, walnuts, pineapple, tomatoes, eggplant, kiwi fruit and plums before taking this test since these foods contain serotonin.

How long does it take to get results from a chromogranin test?

A Chromogranin A Serum Test is used to detect neuroendocrine cancers. Preparation: No special preparation required. Test Results: 3-4 days.

Do I have to fast for chromogranin a test?

These types of tests measure the amount of gastrin, sugar, VIP, or somatostatin in the blood. Patients may need to fast for at least 8 hours for these tests.

Do I need to fast for chromogranin a test?

Measurements may vary with meal consumption, so patients are required to fast before a CgA test. CgA tests are performed every 3 to 6 months. *CgA is a protein found in carcinoid tumor cells, and it may be secreted into the blood. A blood sample is taken, and the level of CgA in the bloodstream is determined.