What is the standard test for detecting cervical cancer?
The Pap test (or Pap smear) looks for precancers, cell changes on the cervix that might become cervical cancer if they are not treated appropriately. The HPV test looks for the virus (human papillomavirus) that can cause these cell changes.
What biomarkers are used to detect cervical cancer?
Serum tumor biomarkers such as Carcinoembryonic antigen (CEA), squamous cell carcinoma antigen (SCC Ag) as well as CA19-9 have been frequently used for detecting and monitoring cervical cancer, because they can be measured non-invasively in blood samples10,11,12,13,14.
What is an early detection tool for cervical cancer?
* PAPANICOLAU (PAP) TEST The PAP test is the more commonly available cervical cancer early detection test. The test involves a gynecological examination by a medical provider, who takes a sample of cells from the cervix.
Can a scan detect cervical cancer?
Imaging tests After a physical exam, a CT scan may be performed to locate a tumor before surgery. A CT scan may also be used to determine tumor size, what other organs might be affected and whether lymph nodes are enlarged. PET/CT scan: Your doctor may order a PET/CT scan as part of the evaluation for cervical cancer.
Can ca125 detect cervical cancer?
In conclusion, CEA, CA 125, and CA 19.9 are useful markers for detection of cervical cancer and monitorization of clinical course of disease. CA 19.9 and CA 125 have been shown to be particularly useful in patients with adenocarcinoma.
Is HPV a biomarker?
In clinical practice, HPV-associated cancers are often diagnosed at late stages, since the disease progress asymptomatically, but antibody levels can predate overt cancer presentation by years5. Therefore, HPV16 E7 antibody has a potential as a blood-based biomarker for HPV-associated cancers6.
Is Stage 1 cervical cancer curable?
Following a staging evaluation, a stage I cancer is said to exist if the cancer is confined to the cervix. Stage I cervical cancer is curable for the majority of patients if surgery, radiation, and chemotherapy are appropriately used.