What is the spectrophotometric analysis of aspirin?
SPECTROPHOTOMETRIC ANALYSIS OF ASPIRIN. Introduction: A colored complex is formed between aspirin and the iron (III) ion. The intensity of the color is directly related to the concentration of aspirin present; therefore, spectrophotometric analysis can be used.
What is spectrophotometric analysis?
(spek″trŏ-fōt″ŏ-me′trik) Determination of materials in a substance or mixture by measuring the amount of light they absorb in the infrared, visible, or ultraviolet region of the spectrum.
What is the wavelength of aspirin?
270 nm
In the US pharmacopoeia and Japanese pharmacopoeia (dissolution test), the analytical wavelength for aspirin is specified as 270 nm. However, by also including the measurement at the wavelength of 205 nm, the presence of decomposition product such as salicylic acid or additives can be confirmed.
What wavelength does aspirin absorb at?
525 nm
acetylsalicylic acid (aspirin) used up: Sodium salicylate will then be reacted with acidic Fe3+ to form salicylatoiron(III) complex, [FeSal]+. This complex displays a maximum absorption at a wavelength of 525 nm and has a purplish red color.
How do you calculate aspirin?
The amount of aspirin can be determined by brominating using KBrO3-KBr mixture. A definite amount of aspirin is refluxed with NaOH. Then salicylic acid is formed. The excess brominating mixture formed is titrated with standard thio.
Where is spectrophotometric analysis used?
Spectrophotometry is widely used for quantitative analysis in various areas (e.g., chemistry, physics, biology, biochemistry, material and chemical engineering, clinical applications, industrial applications, etc). Any application that deals with chemical substances or materials can use this technique.
How is aspirin measured?
The purity and amount of acetylsalicylic acid in aspirin can be measured using a Visual Spectrophotometer.
What are the four properties of aspirin?
Properties of Aspirin
- Its molar mass is 180.16 g/mol.
- Its melting point is 136 ℃.
- Its boiling point is 140 ℃.
- It’s soluble in water. 3g of aspirin can dissolve in 1 liter of water.
- It is a white crystalline solid at room temperature.
- It is weakly acidic in nature.
- Its density is 1.40 g.