Why was the DNA sequence of Anopheles gambiae performed in 2002?
The Anopheles gambiae PEST strain was chosen for genome sequencing because it had both a fixed, standard chromosomal arrangement and a sex-linked pink eye mutation that could readily be used as an indicator of cross-colony contamination (Holt et al 2002: PMID 12364791).
What is the size of Anopheles mosquito?
In comparison to other species, adults are considered small to medium-sized mosquitoes with average wing length varying from 2.8 to 4.4 mm (Gillies and de Meillon 1968). Figure 3. Adult female African malaria mosquito, Anopheles gambiae Giles.
How many base pairs are in the mosquito genome?
gambiae and assembled into scaffolds that span 278 million base pairs. A total of 91% of the genome was organized in 303 scaffolds; the largest scaffold was 23.1 million base pairs.
Why is Anopheles gambiae a study organism of interest?
MOSQUITO IMMUNITY TO THE MALARIA PARASITE Anopheles gambiae, the insect vector of human malaria, has evolved into a unique model system for the study of innate immunity, mainly because of advances in the functional genomics of this organism.
Who is the father of genomics?
Frederick Sanger
Frederick Sanger, ‘the father of genomics’, was one of just four scientists to win two Nobel prizes and the only one to receive both in chemistry. Both were awarded for the invention of methods to determine the order of the biological building blocks of life.
What is the chromosome number of dog?
78 chromosomes
While a human has 46 chromosomes (23 pairs), a cat has 38 chromosomes (19 pairs) and a dog has 78 chromosomes (39 pairs). The exception to this rule is sperm cells and egg cells.
How many genes are in each genome of Anopheles gambiae?
The Anopheles gambiae complete genome sequence of the strain PEST was published in 2002. It contains about 280 Mb, and approximately 12,800 protein-coding genes.
How do female mosquitoes get pregnant?
Some species of female mosquitoes lay eggs directly on the water, while others lay eggs in small depressions where water can collect. In some cases, eggs laid outside of water can survive many years before hatching. After exposure to water, most eggs hatch within 24-72 hours. Once eggs hatch, larvae emerge.