What causes over secretion of growth hormones?
Overproduction of growth hormone is almost always caused by a noncancerous (benign) pituitary tumor (adenoma). Certain rare tumors of the pancreas and lungs also can produce hormones that stimulate the pituitary to produce excessive amounts of growth hormone, with similar consequences.
What are the side effects of too much growth hormone?
Possible side effects of excess hGH injections include:
- carpal tunnel syndrome.
- nerve, muscle, or joint pain.
- swelling of the arms and legs from fluid retention (edema)
- high cholesterol levels.
- numb and tingling skin.
- an increased risk of heart disease and diabetes.
- growth of cancerous tumors.
What effect does growth hormone have in adults?
Growth hormone therapy in adults has been shown to improve exercise performance, oxygen consumption and cardiac output that is likely to be due to its direct beneficial effects on skeletal and heart muscle. Growth hormone therapy has been shown to improve blood lipid profile, especially when combined with a statin.
Is growth hormone secreted in adults?
Integration of all the factors that affect growth hormone synthesis and secretion lead to a pulsatile pattern of release. Basal concentrations of growth hormone in blood are very low. In children and young adults, the most intense period of growth hormone release is shortly after the onset of deep sleep.
What happens when a hormone is overproduced?
In adults, excessive growth hormone for a long period of time produces a condition known as acromegaly in which patients have swelling of the hands and feet and altered facial features. These patients also have organ enlargement and serious functional disorders such as high blood pressure, diabetes and heart disease.
What happens if growth hormone is high?
When you have too much growth hormone, your bones increase in size. In childhood, this leads to increased height and is called gigantism. But in adulthood, a change in height doesn’t occur. Instead, the increase in bone size is limited to the bones of your hands, feet and face, and is called acromegaly.
Which hormone is responsible for height?
Growth hormone is produced by our brain’s pituitary gland and governs our height, bone length and muscle growth.