Is amantadine used for EPS?

Is amantadine used for EPS?

Amantadine was found to be comparable in effect to benztropine mesylate, but with fewer side effects. The potential role of amantadine may be in the treatment of patients with druginduced EPS for whom medication with anticholinergic properties is contraindicated.

What are the doses of amantadine?

Adults—200 milligrams (mg) or 4 teaspoonfuls once a day as a single dose. Older adults—100 milligrams (mg) once a day as a single dose. Children 9 to 12 years of age—100 milligrams (mg) or 2 teaspoonfuls 2 times a day.

How do you titrate amantadine?

Attention-deficit/hyperactivity disorder (ADHD): Limited data available: Oral: Immediate release: Children ≥5 years and Adolescents: Initial: 50 mg/day; titrate up at 4 to 7 day intervals in 50 mg increments to effect; reported range: 50 to 150 mg/day in divided doses 1 to 3 times daily (morning, noon, and 4 PM); …

How does amantadine work for Parkinson’s?

In the treatment of Parkinson disease, studies have shown amantadine acts on dopamine neurons. Amantadine is a weak, non-competitive antagonist of the NMDA receptor, which increases dopamine release and prevents dopamine reuptake.

What time of day should you take amantadine?

The extended-release capsules are usually taken once a day at bedtime. The extended-release tablets are usually taken once a day in the morning. Take amantadine at around the same time(s) every day.

How long should you take amantadine?

This medicine should be taken for at least 2 days after all your flu symptoms have disappeared. This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times at day and night.

Is amantadine poisoning curable?

There is no known antidote. Although some of the manifestations of toxicity are caused by the anticholinergic effects of amantadine, physostigmine should not be used if there is evidence of cardiac conduction disturbance (eg, wide QRS).

When is the best time to take amantadine?