What is Plummer-Vinson syndrome associated with?
Plummer-Vinson syndrome is a condition that can occur in people with long-term (chronic) iron deficiency anemia. People with this condition have problems swallowing due to small, thin growths of tissue that partially block the upper food pipe (esophagus).
How is Plummer-Vinson syndrome diagnosed?
In patients with suspected Plummer-Vinson syndrome (PVS), obtain complete blood cell (CBC) counts, peripheral blood smears, and iron studies (eg, serum iron, total iron-binding capacity [TIBC], ferritin, saturation percentage) to confirm iron deficiency, with or without hypochromic microcytic anemia.
What is sideropenic dysphagia?
Listen to pronunciation. (SIH-der-oh-PEE-nik dis-FAY-jee-uh) A disorder marked by anemia caused by iron deficiency, and a web-like growth of membranes in the throat that makes swallowing difficult. Having sideropenic dysphagia may increase the risk of developing esophageal cancer.
What is the difference between esophageal web and ring?
Rings are bands of normal esophageal tissue that form constrictions around the inside of the esophagus. They occur in the lower esophagus. Webs, which arise in the upper esophagus, are thin layers of cells that grow across the inside of the esophagus. Either condition may make it difficult to swallow solid food.
Is Plummer Vinson syndrome reversible?
Plummer-Vinson syndrome can be treated easily and effectively with iron supplementation and mechanical dilation.
Who gets Plummer Vinson?
[1] Plummer Vinson syndrome is more common in middle-aged women who appear to be at an increased risk of developing squamous cell carcinoma of the pharynx and proximal esophagus.
What clinical signs are typical for Sideropenic syndrome?
The most common among the latter are sores in the corners of the mouth, small atrophic lips, smooth, red tongue with pa- pillar atrophy, dysphagia and fingernail changes (koilonychia, brittle nails).
Can Plummer Vinson syndrome be cured?
Plummer-Vinson syndrome can be treated effectively with iron supplementation and mechanical dilation. In case of significant obstruction of the esophageal lumen by esophageal web and persistent dysphagia despite iron supplementation, rupture and dilation of the web are necessary.
What is the treatment of Plummer Vinson syndrome?
Is Plummer-Vinson syndrome reversible?