What is the drug of choice for acute attack of migraine?

What is the drug of choice for acute attack of migraine?

Currently, for the acute treatment of migraine attacks, non-steroidal anti-inflammatory drugs (NSAIDs) and triptans (serotonin 5HT1B/1D receptor agonists) are recommended. Before intake of NSAID and triptans, metoclopramide or domperidone is useful. In very severe attacks, subcutaneous sumatriptan is first choice.

What is the most effective triptan for migraine?

Among oral medications, eletriptan at a 40-milligram (mg) dose had the highest effectiveness compared with all oral medications. Naratriptan (2.5 mg) had the lowest effectiveness among other oral triptans. Subcutaneous (under the skin) injection was more effective than oral medications.

What is first-line treatment for migraine?

Acetaminophen and nonsteroidal anti-inflammatory drugs are first-line treatments for mild to moderate migraines, whereas triptans are first-line treatments for moderate to severe migraines.

How do triptans help migraines?

Ideally, the oral or intranasal triptans should be used as follows. Take 1 tablet (or administer 1 spray) for early/mild headache. This dose may be repeated after 2 hours. Do not use more than 2 doses within a 24-hour period, and do not use the triptans more than 2 days/week on a chronic basis.

How do you treat acute migraines?

Triptans are effective and safe for treatment of acute migraine. Abortive therapy should be used as early as possible in the course of a migraine. Combination analgesics containing aspirin, caffeine, and acetaminophen are an effective first-line abortive treatment for migraine.

How fast do triptans work?

Triptans taken by mouth are designed to work rapidly – within an hour or so. Injected triptans usually work in 10-15 minutes. After you have taken the first dose: If the triptan worked to relieve your headache but then the headache returned later, you can repeat the dose after 2-4 hours.

What pressure points get rid of migraines?

Pressure Point LI-4 (Hegu) Doing acupressure on this point to relieve pain and headaches. Find pressure point LI-4 by placing your thumb in the space between the base of your thumb and index finder (see Figure 1). Press down on this point for 5 minutes. Move your thumb in a circle while applying pressure.