What drug is used for megaloblastic anemia?
Drugs used to treat Anemia, Megaloblastic
| Drug name | Rating | Rx/OTC |
|---|---|---|
| Generic name: folic acid systemic Brand names: Folacin-800, FA-8 Drug class: vitamins For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information | ||
| View information about Folacin-800 Folacin-800 | Rate | Rx/OTC |
What deficiency can cause megaloblastic anemia?
Either a lack of vitamin B-12 or a lack of folate causes a type of anemia called megaloblastic anemia (pernicious anemia). With these types of anemia, the red blood cells don’t develop normally.
What are the causes of megaloblastic anemia?
Usually, megaloblastic anemia is due to acquired deficiency in vitamin B12 or folic acid. The deficiency can be related to inadequate dietary intake of these B vitamins or poor intestinal absorption.
Why folic acid is not given alone in megaloblastic anemia?
Folic acid should never be given alone in the treatment of Addisonian pernicious anaemia and other vitamin B12 deficiency states because it may precipitate the onset of subacute combined degeneration of the spinal cord.
How does a deficiency of folate or vitamin B12 contribute to megaloblastic anemia?
The two most common causes of megaloblastic anemia are deficiencies of vitamin B12 and folate. These two nutrients are necessary for producing healthy RBCs. When you don’t get enough of them, it affects the makeup of your RBCs. This leads to cells that don’t divide and reproduce the way they should.
How serious is megaloblastic anemia?
Today, people with megaloblastic anemia due to either vitamin B12 or folate deficiency can manage their symptoms and feel better with ongoing treatment and dietary supplements. Vitamin B12 deficiency can lead to other problems. These can include nerve damage, neurological problems, and digestive tract problems.
What happens if you have megaloblastic anemia?
Individuals with megaloblastic anemia may also develop gastrointestinal abnormalities including diarrhea, nausea, and loss of appetite. Some affected individuals may develop a sore, reddened tongue. These abnormalities may result in unintended weight loss.