What is the karyotype for a male with Down syndrome?

What is the karyotype for a male with Down syndrome?

Chromosome picture (karyotype) from a male (46,XY). Most individuals have the same chromosome makeup in all the cells in their body. People with Down syndrome as a result of mosaicism have some cells in the body with the usual two copies of chromosome 21, and other cells with three copies of chromosome 21.

How is the karyotype of a person with Down syndrome different to a normal karyotype?

These are the chromosomes of a normal karyotype. Try pairing the chromosomes yourself (as has been done for the Down Syndrome karyotype below). Down Syndrome results when three, rather than the normal two, copies of chromosome 21 are present in each cell.

Does the male or female determine Down syndrome?

Overall, the two sexes are affected roughly equally. The male-to-female ratio is slightly higher (approximately 1.15:1) in newborns with Down syndrome, but this effect is restricted to neonates with free trisomy 21.

What is karyotype 47 XY?

Human karyotypes for teaching: (47, XY,+21, Trisomy 21) These karyotypes are from abnormal males. There is a full set of 23 homologous pairs of autosomes, and an X and Y, but an extra chromosome 21. These individuals are also said to have Down syndrome.

What would a karyotype of someone with Down syndrome look like?

The number 46 indicates that there were 46 chromosomes present, and the XX indicates there were two X chromosomes so the person is female. If the individual was a boy, it would say 46, XY. If your child has been diagnosed with Down syndrome, the karyotype image would have an extra copy of chromosome 21 as seen below.

What are the two types of disorders of human where the karyotype is 47?

XYY syndrome is a rare chromosomal disorder caused by the presence of an extra Y chromosome. Normally, males have 46 chromosomes including one X and one Y chromosome. Males with XYY syndrome have 47 chromosomes, two of which are Y chromosomes.