What does refractory mean in medical terms?

What does refractory mean in medical terms?

(reh-FRAK-tor-ee) In medicine, describes a disease or condition that does not respond to treatment.

What is the meaning of refractory symptoms?

A refractory symptom is one that cannot be adequately controlled despite aggressive efforts to identify a tolerable therapy that does not compromise consciousness (Cherny 1994). A refractory symptom may be subjective and, at times, nonspecific.

What are refractory symptoms in heart failure?

Refractory CHF is defined as symptoms of CHF at rest or repeated exacerbations of CHF despite “optimal” triple-drug therapy. Most patients with refractory CHF require hemodynamic monitoring and treatment in the intensive care unit.

What is refractory gastrointestinal symptoms?

The symptoms of refractory disease are not unlike those of untreated celiac disease except that they are usually more severe and more disabling. The more common symptoms include weight loss, diarrhea, abdominal pain, malnutrition and anemia.

Whats the definition of refractory?

1 : resisting control or authority : stubborn, unmanageable. 2a : resistant to treatment or cure a refractory lesion. b : unresponsive to stimulus. c : immune, insusceptible after recovery they were refractory to infection.

What does refractory pain mean?

Intractable pain or refractory pain occurs when pain cannot be adequately controlled despite aggressive measures.

What is refractory psychosis?

Refractory psychosis can be present from the first episode, or it can develop after years of prolonged response to antipsychotic treatment with periods of remission. The cause of psychosis in those whose psychotic symptoms respond to typical antipsychotics may involve enhanced release of dopamine.

What class is end stage heart failure?

Patients with end stage heart failure fall into stage D of the ABCD classification of the American College of Cardiology (ACC)/American Heart Association (AHA), and class III–IV of the New York Heart Association (NYHA) functional classification; they are characterised by advanced structural heart disease and pronounced …

What is refractory pain?

Do all PPIs cause anxiety?

People taking a PPI were about twice as likely as other individuals to report depression or anxiety. The authors conclude: “Use of PPIs might represent a frequent cause of depression in older populations; thus, mood should be routinely assessed in elderly patients on PPIs.”